1) I'm stuck with trying to do anything like putting TomTom on my Avic-S1. Whatever I try to do it doesn't work with Vista. Also, the new Microsoft Mobile Device for Vista won't recognize the Avic.
2) I'm also guessing that you have to have a brand new unused SD card also?
Yep, you are stuck.
I couldn't get the avic-s1 working with vista either.
I ended up getting VMWare demo for 30 days and building an XP image.
Once I got this up and running, I could manage my avic.
For your question 2, you could just format a SD card in FAT format, not FAT32 or NTFS.
iceblue68 did u try to sync your PC with AVIC by "Microsoft ActiveSync" ?
Yeah, with Vista you can only use Microsoft Mobile Device Center, which won't recognize the Pioneer. The version of CE is to old on it. I'm now going to try to put Mio on my S1 via my work laptop which is still on XP Pro.
So how can i connect my S2 to PC with Vista?
Look at my post from feb 25th,, there s the link also,,
1) I'm stuck with trying to do anything like putting TomTom on my Avic-S1. Whatever I try to do it doesn't work with Vista. Also, the new Microsoft Mobile Device for Vista won't recognize the Avic.
2) I'm also guessing that you have to have a brand new unused SD card also?
You must use Windows XP only !!!!!!!!!!!!! Not compaible with Vista !!!!!!!!
Best way is just to use SD card reader to transfer files you need to SD card 
Or The best way to have capability with all programs that dont want to run on Vista is to download from Microsoft web site "Virtual PC 2007" its free and you can run different OS at the same time on 1 PC