The D3 doesn't use reverse or speed wires to lock out functionality while the car is in motion--so it has nothing to do with the bypass at all. In fact, it only uses the parking brake wire, which can be grounded if the other modification is made to the pin on the RCA harness.
You SHOULD definitely hook up both the reverse and speed wires. Without the speed wire in particular, the D3 is unable to accurately determine your position. It will work without them, but not as well.