i was able to format at SDXC card (micro in an SD adapter) using the NTFS file system (a trick for this mac guy but easy if yo are running Windows) and my Pioneer 4500NEX recognizes it fine. i have just over 10,000 tracks using up 249gb of the space. i couldn't get FAT32 to work (that would have made things easier on the Mac side of things)
let me know if you have any questions. i don't know if it will work with older NEX units, but i believe it works on the 4400,8400,4500,8500 based on my limited research.